Atherosclerosis is a complex process that is seen as an inflammation response to injury and involves the interaction of numerous cell types with formation of fatty streaks that progress to, plaque destabilization, and rupture.
Initially, there are generally no symptoms. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which arteries are affected. Symptoms generally do not begin until middle age.
Atherosclerosis refers to the buildup of fats, cholesterol, and other substances in and on your artery walls (plaque), which can restrict blood flow. The plaque can burst, triggering a blood clot. Although atherosclerosis is often considered a heart problem, it can affect arteries anywhere in your body.
CVD is leading cause of death worldwide. Accumulating evidence suggests that astaxanthin may work by inhibiting LDL (bad cholesterol) and decreasing trans fats (caused by food preservatives) and increasing HDL (good cholesterol). Along with astaxanthin’s ability to reduce oxidative stress (free radicals causing inflammation) and balancing these lipoproteins – LDL and HDL – astaxanthin may prove to be a strong preventive for heart disease.